2446-83-5

Purification Methods

Purify the azo compound by distillation at as high a vacuum as possible. Since it is likely to explode, use an oil bath for heating the still, and all operations should be carried out behind an adequate shield. [Kauer Org Synth Coll Vol IV 412 1963, Beilstein 3 III 233]. This reagent is useful in the Mitsunobu reaction [Mitsunobu Synthesis 1 1981, Gennari et al. J Am Chem Soc 108 6394 1986, Evans et al. J Am Chem Soc 108 6394 1986, Hughes Org React 42 335 1992, Dodge et al. Org Synth 73 110 1996, Hughes Org Prep Proc Int 28 127 1996, Ferguson & Marcelle J Am Chem Soc 128 4576 2006; see also di-tert-butyl azodicarboxylate and DEAD above].

Product description

Isopropyl azodicarboxylate (Acronym DIAD; foaming agent DIPA) belongs to diisopropyl azo-hydroxy acid salt. At room temperature, it is an orange-red transparent oily liquid with special smell and is soluble in almost all organic solvents and plasticizers. It is also insoluble in water but soluble in common plasticizer. It can be well miscible with plastic with good thermal stability. Storage stability: the decomposition substance is colorless, non-toxic, non-pollution, non-blooming and odorless. In the range of 40~120 °C, it can obtain high gas evolution. It is also the liquid blowing agent of vinyl resin and can be used to make light-colored vinyl foam. It has a uniform pore structure, with different formulations and processing conditions obtaining the foam of either closed pore or open pore. It can also be used as pharmaceutical intermediates and organic synthesis reagents. The above information is edited by the lookchem of Dai Xiongfeng.

General Description

Reacted with dioxaphosphorinanes and iron catalyst to generate rearranged phosphonium ylide products.